Run Enrichment Analysis (Over-representation Analysis)
RunEnrichment.RdRun enrichment analysis on a list of differentially expressed genes (DEGs)
Usage
RunEnrichment(
degs,
deg = "p_val_adj < 0.05",
dbs = "KEGG_2021_Human",
cache = NULL,
error = TRUE,
site = "Enrichr",
...
)Arguments
- degs
A data frame of DEGs, typically generated by
RunSeuratDEAnalysis- deg
A string specifying the condition for a gene to be considered as differentially expressed
- dbs
A string specifying the database to use for enrichment analysis A list of available databases can be found at https://maayanlab.cloud/Enrichr/#libraries
- cache
A string specifying the directory to cache the results Set to
FALSEto disable caching- error
A boolean specifying whether to throw an error if the enrichment analysis fails
- site
A string specifying the Enrichr site to use
- ...
Additional arguments to pass to RunEnrichment
Examples
# \donttest{
degs <- suppressWarnings(RunSeuratDEAnalysis(SeuratObject::pbmc_small,
"groups", "g1", "g2"))
RunEnrichment(degs, deg = "abs(avg_log2FC) > 1")
#> Connection changed to https://maayanlab.cloud/Enrichr/
#> Connection is Live!
#> Uploading data to Enrichr... Done.
#> Querying KEGG_2021_Human... Done.
#> Parsing results... Done.
#> Term Overlap
#> 1 Hematopoietic cell lineage 8/99
#> 2 Graft-versus-host disease 3/42
#> 3 Type I diabetes mellitus 3/43
#> 4 Tuberculosis 5/180
#> 5 Leishmaniasis 3/77
#> 6 B cell receptor signaling pathway 3/81
#> 7 IL-17 signaling pathway 3/94
#> 8 Staphylococcus aureus infection 3/95
#> 9 Neutrophil extracellular trap formation 4/189
#> 10 Asthma 2/31
#> 11 Amoebiasis 3/102
#> 12 Toll-like receptor signaling pathway 3/104
#> 13 NF-kappa B signaling pathway 3/104
#> 14 Epstein-Barr virus infection 4/202
#> 15 Allograft rejection 2/38
#> 16 Sphingolipid signaling pathway 3/119
#> 17 Human cytomegalovirus infection 4/225
#> 18 Osteoclast differentiation 3/127
#> 19 Natural killer cell mediated cytotoxicity 3/131
#> 20 Autoimmune thyroid disease 2/53
#> 21 Legionellosis 2/57
#> 22 Phagosome 3/152
#> 23 Viral myocarditis 2/60
#> 24 Necroptosis 3/159
#> 25 Cytosolic DNA-sensing pathway 2/63
#> 26 Inflammatory bowel disease 2/65
#> 27 Cytokine-cytokine receptor interaction 4/295
#> 28 Influenza A 3/172
#> 29 Pertussis 2/76
#> 30 Chemokine signaling pathway 3/192
#> 31 PI3K-Akt signaling pathway 4/354
#> 32 Lipid and atherosclerosis 3/215
#> 33 Rheumatoid arthritis 2/93
#> 34 Viral protein interaction with cytokine and cytokine receptor 2/100
#> 35 Th17 cell differentiation 2/107
#> 36 Systemic lupus erythematosus 2/135
#> 37 Fluid shear stress and atherosclerosis 2/139
#> 38 Measles 2/139
#> 39 Apoptosis 2/142
#> 40 Pentose phosphate pathway 1/30
#> 41 Non-alcoholic fatty liver disease 2/155
#> 42 Cellular senescence 2/156
#> 43 Herpes simplex virus 1 infection 4/498
#> 44 Nicotinate and nicotinamide metabolism 1/35
#> 45 Hepatitis B 2/162
#> 46 African trypanosomiasis 1/37
#> 47 Primary immunodeficiency 1/38
#> 48 Neuroactive ligand-receptor interaction 3/341
#> 49 Ferroptosis 1/41
#> 50 NOD-like receptor signaling pathway 2/181
#> 51 Porphyrin and chlorophyll metabolism 1/43
#> 52 Basal transcription factors 1/45
#> 53 Alzheimer disease 3/369
#> 54 Transcriptional misregulation in cancer 2/192
#> 55 Kaposi sarcoma-associated herpesvirus infection 2/193
#> 56 Intestinal immune network for IgA production 1/48
#> 57 Cholesterol metabolism 1/50
#> 58 Malaria 1/50
#> 59 Focal adhesion 2/201
#> 60 Rap1 signaling pathway 2/210
#> 61 Pyrimidine metabolism 1/56
#> 62 Human immunodeficiency virus 1 infection 2/212
#> 63 Human T-cell leukemia virus 1 infection 2/219
#> 64 Acute myeloid leukemia 1/67
#> 65 Fc epsilon RI signaling pathway 1/68
#> 66 Shigellosis 2/246
#> 67 p53 signaling pathway 1/73
#> 68 Salmonella infection 2/249
#> 69 Thyroid hormone synthesis 1/75
#> 70 Arrhythmogenic right ventricular cardiomyopathy 1/77
#> 71 Antigen processing and presentation 1/78
#> 72 RNA degradation 1/79
#> 73 Pathways of neurodegeneration 3/475
#> 74 Prion disease 2/273
#> 75 ECM-receptor interaction 1/88
#> 76 GABAergic synapse 1/89
#> 77 Hypertrophic cardiomyopathy 1/90
#> 78 Morphine addiction 1/91
#> 79 Small cell lung cancer 1/92
#> 80 Th1 and Th2 cell differentiation 1/92
#> 81 Dilated cardiomyopathy 1/96
#> 82 MAPK signaling pathway 2/294
#> 83 Circadian entrainment 1/97
#> 84 Fc gamma R-mediated phagocytosis 1/97
#> 85 Inflammatory mediator regulation of TRP channels 1/98
#> 86 AGE-RAGE signaling pathway in diabetic complications 1/100
#> 87 Chagas disease 1/102
#> 88 C-type lectin receptor signaling pathway 1/104
#> 89 Pathways in cancer 3/531
#> 90 Ribosome biogenesis in eukaryotes 1/108
#> 91 TNF signaling pathway 1/112
#> 92 Toxoplasmosis 1/112
#> 93 Serotonergic synapse 1/113
#> 94 Cholinergic synapse 1/113
#> 95 Glutamatergic synapse 1/114
#> 96 Platelet activation 1/124
#> 97 Purine metabolism 1/129
#> 98 Relaxin signaling pathway 1/129
#> 99 FoxO signaling pathway 1/131
#> 100 Dopaminergic synapse 1/132
#> 101 Amyotrophic lateral sclerosis 2/364
#> 102 Apelin signaling pathway 1/137
#> 103 Yersinia infection 1/137
#> 104 Spinocerebellar ataxia 1/143
#> 105 Cell adhesion molecules 1/148
#> 106 Phospholipase D signaling pathway 1/148
#> 107 Retrograde endocannabinoid signaling 1/148
#> 108 Spliceosome 1/150
#> 109 Hepatitis C 1/157
#> 110 cGMP-PKG signaling pathway 1/167
#> 111 Tight junction 1/169
#> 112 Alcoholism 1/186
#> 113 RNA transport 1/186
#> 114 Pathogenic Escherichia coli infection 1/197
#> 115 Viral carcinogenesis 1/203
#> 116 Diabetic cardiomyopathy 1/203
#> 117 Regulation of actin cytoskeleton 1/218
#> 118 Coronavirus disease 1/232
#> 119 Ras signaling pathway 1/232
#> 120 Calcium signaling pathway 1/240
#> 121 Parkinson disease 1/249
#> 122 Endocytosis 1/252
#> 123 Huntington disease 1/306
#> 124 Human papillomavirus infection 1/331
#> P.value Adjusted.P.value Old.P.value Old.Adjusted.P.value Odds.Ratio
#> 1 3.864191e-09 4.791597e-07 0 0 25.6405947
#> 2 5.441297e-04 1.908538e-02 0 0 20.9536354
#> 3 5.833473e-04 1.908538e-02 0 0 20.4287671
#> 4 6.156575e-04 1.908538e-02 0 0 7.9472837
#> 5 3.152458e-03 6.515878e-02 0 0 11.0236949
#> 6 3.637281e-03 6.515878e-02 0 0 10.4562698
#> 7 5.516829e-03 6.515878e-02 0 0 8.9566461
#> 8 5.681341e-03 6.515878e-02 0 0 8.8588446
#> 9 5.837599e-03 6.515878e-02 0 0 5.9276276
#> 10 6.170140e-03 6.515878e-02 0 0 18.5414725
#> 11 6.915482e-03 6.515878e-02 0 0 8.2295558
#> 12 7.295013e-03 6.515878e-02 0 0 8.0657806
#> 13 7.295013e-03 6.515878e-02 0 0 8.0657806
#> 14 7.356637e-03 6.515878e-02 0 0 5.5347924
#> 15 9.169706e-03 7.580290e-02 0 0 14.9309309
#> 16 1.053421e-02 7.763074e-02 0 0 7.0174776
#> 17 1.064292e-02 7.763074e-02 0 0 4.9529915
#> 18 1.255218e-02 8.647057e-02 0 0 6.5620857
#> 19 1.363853e-02 8.900938e-02 0 0 6.3557363
#> 20 1.732811e-02 1.074343e-01 0 0 10.5315315
#> 21 1.987498e-02 1.138674e-01 0 0 9.7636364
#> 22 2.020228e-02 1.138674e-01 0 0 5.4541693
#> 23 2.188161e-02 1.173583e-01 0 0 9.2572227
#> 24 2.271451e-02 1.173583e-01 0 0 5.2075869
#> 25 2.396862e-02 1.188844e-01 0 0 8.8006203
#> 26 2.540362e-02 1.193474e-01 0 0 8.5203775
#> 27 2.598693e-02 1.193474e-01 0 0 3.7481863
#> 28 2.781207e-02 1.231677e-01 0 0 4.8038421
#> 29 3.389234e-02 1.449190e-01 0 0 7.2498174
#> 30 3.674508e-02 1.518797e-01 0 0 4.2911503
#> 31 4.584599e-02 1.833840e-01 0 0 3.1069841
#> 32 4.862084e-02 1.834801e-01 0 0 3.8211424
#> 33 4.882938e-02 1.834801e-01 0 0 5.8904069
#> 34 5.555659e-02 2.026182e-01 0 0 5.4677330
#> 35 6.258860e-02 2.217425e-01 0 0 5.1014157
#> 36 9.337261e-02 3.200272e-01 0 0 4.0217435
#> 37 9.807285e-02 3.200272e-01 0 0 3.9035313
#> 38 9.807285e-02 3.200272e-01 0 0 3.9035313
#> 39 1.016415e-01 3.231679e-01 0 0 3.8193050
#> 40 1.080095e-01 3.348295e-01 0 0 9.1471264
#> 41 1.175045e-01 3.480007e-01 0 0 3.4924925
#> 42 1.187498e-01 3.480007e-01 0 0 3.4696385
#> 43 1.212348e-01 3.480007e-01 0 0 2.1851102
#> 44 1.248558e-01 3.480007e-01 0 0 7.8000000
#> 45 1.262906e-01 3.480007e-01 0 0 3.3385135
#> 46 1.315060e-01 3.544944e-01 0 0 7.3659259
#> 47 1.348124e-01 3.556752e-01 0 0 7.1664865
#> 48 1.401998e-01 3.621827e-01 0 0 2.3813731
#> 49 1.446572e-01 3.660713e-01 0 0 6.6280000
#> 50 1.508671e-01 3.675236e-01 0 0 2.9812774
#> 51 1.511589e-01 3.675236e-01 0 0 6.3117460
#> 52 1.576118e-01 3.702298e-01 0 0 6.0242424
#> 53 1.653864e-01 3.702298e-01 0 0 2.1960476
#> 54 1.655039e-01 3.702298e-01 0 0 2.8071124
#> 55 1.668471e-01 3.702298e-01 0 0 2.7922739
#> 56 1.672006e-01 3.702298e-01 0 0 5.6388652
#> 57 1.735331e-01 3.710019e-01 0 0 5.4081633
#> 58 1.735331e-01 3.710019e-01 0 0 5.4081633
#> 59 1.776604e-01 3.733879e-01 0 0 2.6789352
#> 60 1.899537e-01 3.854038e-01 0 0 2.5618503
#> 61 1.922471e-01 3.854038e-01 0 0 4.8167273
#> 62 1.927019e-01 3.854038e-01 0 0 2.5371943
#> 63 2.023614e-01 3.982987e-01 0 0 2.4544775
#> 64 2.254763e-01 4.357730e-01 0 0 4.0117172
#> 65 2.284294e-01 4.357730e-01 0 0 3.9516418
#> 66 2.400637e-01 4.454554e-01 0 0 2.1798848
#> 67 2.430289e-01 4.454554e-01 0 0 3.6762963
#> 68 2.442820e-01 4.454554e-01 0 0 2.1530802
#> 69 2.487921e-01 4.471046e-01 0 0 3.5765766
#> 70 2.545120e-01 4.481030e-01 0 0 3.4821053
#> 71 2.573558e-01 4.481030e-01 0 0 3.4367100
#> 72 2.601889e-01 4.481030e-01 0 0 3.3924786
#> 73 2.699582e-01 4.552048e-01 0 0 1.6936383
#> 74 2.781015e-01 4.552048e-01 0 0 1.9600080
#> 75 2.852114e-01 4.552048e-01 0 0 3.0401533
#> 76 2.879396e-01 4.552048e-01 0 0 3.0054545
#> 77 2.906576e-01 4.552048e-01 0 0 2.9715356
#> 78 2.933652e-01 4.552048e-01 0 0 2.9383704
#> 79 2.960627e-01 4.552048e-01 0 0 2.9059341
#> 80 2.960627e-01 4.552048e-01 0 0 2.9059341
#> 81 3.067514e-01 4.552048e-01 0 0 2.7830175
#> 82 3.076467e-01 4.552048e-01 0 0 1.8171048
#> 83 3.093985e-01 4.552048e-01 0 0 2.7538889
#> 84 3.093985e-01 4.552048e-01 0 0 2.7538889
#> 85 3.120355e-01 4.552048e-01 0 0 2.7253608
#> 86 3.172799e-01 4.572461e-01 0 0 2.6700337
#> 87 3.224848e-01 4.572461e-01 0 0 2.6168977
#> 88 3.276505e-01 4.572461e-01 0 0 2.5658252
#> 89 3.281847e-01 4.572461e-01 0 0 1.5096513
#> 90 3.378657e-01 4.606299e-01 0 0 2.4694081
#> 91 3.479277e-01 4.606299e-01 0 0 2.3799399
#> 92 3.479277e-01 4.606299e-01 0 0 2.3799399
#> 93 3.504195e-01 4.606299e-01 0 0 2.3585714
#> 94 3.504195e-01 4.606299e-01 0 0 2.3585714
#> 95 3.529019e-01 4.606299e-01 0 0 2.3375811
#> 96 3.772170e-01 4.872386e-01 0 0 2.1464499
#> 97 3.890341e-01 4.905620e-01 0 0 2.0620833
#> 98 3.890341e-01 4.905620e-01 0 0 2.0620833
#> 99 3.936988e-01 4.905620e-01 0 0 2.0301538
#> 100 3.960179e-01 4.905620e-01 0 0 2.0145547
#> 101 4.038144e-01 4.905620e-01 0 0 1.4605047
#> 102 4.074829e-01 4.905620e-01 0 0 1.9400000
#> 103 4.074829e-01 4.905620e-01 0 0 1.9400000
#> 104 4.209577e-01 5.005837e-01 0 0 1.8574648
#> 105 4.319553e-01 5.005837e-01 0 0 1.7938322
#> 106 4.319553e-01 5.005837e-01 0 0 1.7938322
#> 107 4.319553e-01 5.005837e-01 0 0 1.7938322
#> 108 4.362964e-01 5.009329e-01 0 0 1.7695749
#> 109 4.512340e-01 5.133304e-01 0 0 1.6895726
#> 110 4.718981e-01 5.316782e-01 0 0 1.5869880
#> 111 4.759378e-01 5.316782e-01 0 0 1.5679365
#> 112 5.090666e-01 5.586218e-01 0 0 1.4226306
#> 113 5.090666e-01 5.586218e-01 0 0 1.4226306
#> 114 5.293925e-01 5.758305e-01 0 0 1.3420408
#> 115 5.401270e-01 5.773771e-01 0 0 1.3017822
#> 116 5.401270e-01 5.773771e-01 0 0 1.3017822
#> 117 5.659174e-01 5.997757e-01 0 0 1.2108756
#> 118 5.886982e-01 6.134334e-01 0 0 1.1366811
#> 119 5.886982e-01 6.134334e-01 0 0 1.1366811
#> 120 6.011817e-01 6.212211e-01 0 0 1.0981869
#> 121 6.147791e-01 6.293601e-01 0 0 1.0578495
#> 122 6.192091e-01 6.293601e-01 0 0 1.0450465
#> 123 6.908733e-01 6.964901e-01 0 0 0.8576612
#> 124 7.193720e-01 7.193720e-01 0 0 0.7916768
#> Combined.Score Genes
#> 1 496.6971266 FCER2;HLA-DMA;IL1B;CD19;ITGA2B;CD14;CD1C;MS4A1
#> 2 157.4942918 HLA-DMA;IL1B;GZMB
#> 3 152.1274703 HLA-DMA;IL1B;GZMB
#> 4 58.7528355 FCGR3A;HLA-DMA;IL1B;CD14;BID
#> 5 63.4917729 FCGR3A;HLA-DMA;IL1B
#> 6 58.7278355 CD79B;CD19;LILRA3
#> 7 46.5741304 IL1B;S100A8;IL17RA
#> 8 45.8052573 FCGR3A;HLA-DMA;FPR1
#> 9 30.4883714 FCGR3A;ITGA2B;VDAC3;FPR1
#> 10 94.3396393 HLA-DMA;FCER1A
#> 11 40.9337495 IL1B;CD14;CD1C
#> 12 39.6881925 IL1B;CCL4;CD14
#> 13 39.6881925 IL1B;CCL4;CD14
#> 14 27.1877438 FCER2;HLA-DMA;CD19;BID
#> 15 70.0536893 HLA-DMA;GZMB
#> 16 31.9514685 FCER1A;BID;S1PR4
#> 17 22.5007466 IL1B;CCL4;BID;GNG11
#> 18 28.7278988 FCGR3A;IL1B;LILRA3
#> 19 27.2969728 FCGR3A;GZMB;BID
#> 20 42.7098384 HLA-DMA;GZMB
#> 21 38.2567922 IL1B;CD14
#> 22 21.2819495 FCGR3A;HLA-DMA;CD14
#> 23 35.3821120 HLA-DMA;BID
#> 24 19.7094217 IL1B;VDAC3;BID
#> 25 32.8351999 IL1B;CCL4
#> 26 31.2941854 HLA-DMA;IL1B
#> 27 13.6814864 IL1B;CCL4;CCR7;IL17RA
#> 28 17.2087329 HLA-DMA;IL1B;BID
#> 29 24.5374866 IL1B;CD14
#> 30 14.1768919 CCL4;CCR7;GNG11
#> 31 9.5771778 TCL1A;CD19;ITGA2B;GNG11
#> 32 11.5539998 IL1B;CD14;BID
#> 33 17.7856301 HLA-DMA;IL1B
#> 34 15.8036792 CCL4;CCR7
#> 35 14.1369007 HLA-DMA;IL1B
#> 36 9.5361862 FCGR3A;HLA-DMA
#> 37 9.0641742 IL1B;ITGA2B
#> 38 9.0641742 IL1B;BID
#> 39 8.7320888 GZMB;BID
#> 40 20.3572579 TALDO1
#> 41 7.4783993 IL1B;BID
#> 42 7.3928857 VDAC3;ZFP36L1
#> 43 4.6106392 HLA-DMA;IL1B;BID;SRSF7
#> 44 16.2286503 NT5C
#> 45 6.9079518 VDAC3;BID
#> 46 14.9432755 IL1B
#> 47 14.3607166 CD19
#> 48 4.6786526 FPR1;S1PR4;PTGDR
#> 49 12.8144994 VDAC3
#> 50 5.6386575 IL1B;VDAC3
#> 51 11.9255625 BLVRA
#> 52 11.1305110 TAF7
#> 53 3.9517238 IL1B;VDAC3;BID
#> 54 5.0493231 GZMB;CD14
#> 55 5.0000618 BID;GNG11
#> 56 10.0854555 HLA-DMA
#> 57 9.4717853 VDAC3
#> 58 9.4717853 IL1B
#> 59 4.6288830 ITGA2B;PARVB
#> 60 4.2551685 ITGA2B;FPR1
#> 61 7.9426568 NT5C
#> 62 4.1777717 BID;GNG11
#> 63 3.9215185 HLA-DMA;VDAC3
#> 64 5.9756141 CD14
#> 65 5.8347105 FCER1A
#> 66 3.1103704 IL1B;CD14
#> 67 5.2003963 BID
#> 68 3.0346201 IL1B;CD14
#> 69 4.9755105 ASGR1
#> 70 4.7649386 ITGA2B
#> 71 4.6646321 HLA-DMA
#> 72 4.5674552 MPHOSPH6
#> 73 2.2177995 IL1B;VDAC3;BID
#> 74 2.5083574 IL1B;VDAC3
#> 75 3.8139466 ITGA2B
#> 76 3.7418041 GNG11
#> 77 3.6716575 ITGA2B
#> 78 3.6034320 GNG11
#> 79 3.5370563 ITGA2B
#> 80 3.5370563 HLA-DMA
#> 81 3.2887409 ITGA2B
#> 82 2.1420090 IL1B;CD14
#> 83 3.2306569 GNG11
#> 84 3.2306569 FCGR3A
#> 85 3.1740594 IL1B
#> 86 3.0651211 IL1B
#> 87 2.9615412 IL1B
#> 88 2.8629674 IL1B
#> 89 1.6820213 ITGA2B;BID;GNG11
#> 90 2.6795714 POP7
#> 91 2.5126468 IL1B
#> 92 2.5126468 HLA-DMA
#> 93 2.4732551 GNG11
#> 94 2.4732551 GNG11
#> 95 2.4347428 GNG11
#> 96 2.0926484 ITGA2B
#> 97 1.9467885 NT5C
#> 98 1.9467885 GNG11
#> 99 1.8924468 S1PR4
#> 100 1.8660736 GNG11
#> 101 1.3243856 BID;SRSF7
#> 102 1.7416472 GNG11
#> 103 1.7416472 IL1B
#> 104 1.6071212 VDAC3
#> 105 1.5058023 HLA-DMA
#> 106 1.5058023 FCER1A
#> 107 1.5058023 GNG11
#> 108 1.4677447 SRSF7
#> 109 1.3445100 BID
#> 110 1.1918157 VDAC3
#> 111 1.1641429 CD1C
#> 112 0.9605267 GNG11
#> 113 0.9605267 POP7
#> 114 0.8535717 IL1B
#> 115 0.8018341 VDAC3
#> 116 0.8018341 VDAC3
#> 117 0.6893601 ITGA2B
#> 118 0.6022610 IL1B
#> 119 0.6022610 GNG11
#> 120 0.5588213 VDAC3
#> 121 0.5146355 VDAC3
#> 122 0.5009036 VPS28
#> 123 0.3171621 VDAC3
#> 124 0.2607599 ITGA2B
#> db
#> 1 KEGG_2021_Human
#> 2 KEGG_2021_Human
#> 3 KEGG_2021_Human
#> 4 KEGG_2021_Human
#> 5 KEGG_2021_Human
#> 6 KEGG_2021_Human
#> 7 KEGG_2021_Human
#> 8 KEGG_2021_Human
#> 9 KEGG_2021_Human
#> 10 KEGG_2021_Human
#> 11 KEGG_2021_Human
#> 12 KEGG_2021_Human
#> 13 KEGG_2021_Human
#> 14 KEGG_2021_Human
#> 15 KEGG_2021_Human
#> 16 KEGG_2021_Human
#> 17 KEGG_2021_Human
#> 18 KEGG_2021_Human
#> 19 KEGG_2021_Human
#> 20 KEGG_2021_Human
#> 21 KEGG_2021_Human
#> 22 KEGG_2021_Human
#> 23 KEGG_2021_Human
#> 24 KEGG_2021_Human
#> 25 KEGG_2021_Human
#> 26 KEGG_2021_Human
#> 27 KEGG_2021_Human
#> 28 KEGG_2021_Human
#> 29 KEGG_2021_Human
#> 30 KEGG_2021_Human
#> 31 KEGG_2021_Human
#> 32 KEGG_2021_Human
#> 33 KEGG_2021_Human
#> 34 KEGG_2021_Human
#> 35 KEGG_2021_Human
#> 36 KEGG_2021_Human
#> 37 KEGG_2021_Human
#> 38 KEGG_2021_Human
#> 39 KEGG_2021_Human
#> 40 KEGG_2021_Human
#> 41 KEGG_2021_Human
#> 42 KEGG_2021_Human
#> 43 KEGG_2021_Human
#> 44 KEGG_2021_Human
#> 45 KEGG_2021_Human
#> 46 KEGG_2021_Human
#> 47 KEGG_2021_Human
#> 48 KEGG_2021_Human
#> 49 KEGG_2021_Human
#> 50 KEGG_2021_Human
#> 51 KEGG_2021_Human
#> 52 KEGG_2021_Human
#> 53 KEGG_2021_Human
#> 54 KEGG_2021_Human
#> 55 KEGG_2021_Human
#> 56 KEGG_2021_Human
#> 57 KEGG_2021_Human
#> 58 KEGG_2021_Human
#> 59 KEGG_2021_Human
#> 60 KEGG_2021_Human
#> 61 KEGG_2021_Human
#> 62 KEGG_2021_Human
#> 63 KEGG_2021_Human
#> 64 KEGG_2021_Human
#> 65 KEGG_2021_Human
#> 66 KEGG_2021_Human
#> 67 KEGG_2021_Human
#> 68 KEGG_2021_Human
#> 69 KEGG_2021_Human
#> 70 KEGG_2021_Human
#> 71 KEGG_2021_Human
#> 72 KEGG_2021_Human
#> 73 KEGG_2021_Human
#> 74 KEGG_2021_Human
#> 75 KEGG_2021_Human
#> 76 KEGG_2021_Human
#> 77 KEGG_2021_Human
#> 78 KEGG_2021_Human
#> 79 KEGG_2021_Human
#> 80 KEGG_2021_Human
#> 81 KEGG_2021_Human
#> 82 KEGG_2021_Human
#> 83 KEGG_2021_Human
#> 84 KEGG_2021_Human
#> 85 KEGG_2021_Human
#> 86 KEGG_2021_Human
#> 87 KEGG_2021_Human
#> 88 KEGG_2021_Human
#> 89 KEGG_2021_Human
#> 90 KEGG_2021_Human
#> 91 KEGG_2021_Human
#> 92 KEGG_2021_Human
#> 93 KEGG_2021_Human
#> 94 KEGG_2021_Human
#> 95 KEGG_2021_Human
#> 96 KEGG_2021_Human
#> 97 KEGG_2021_Human
#> 98 KEGG_2021_Human
#> 99 KEGG_2021_Human
#> 100 KEGG_2021_Human
#> 101 KEGG_2021_Human
#> 102 KEGG_2021_Human
#> 103 KEGG_2021_Human
#> 104 KEGG_2021_Human
#> 105 KEGG_2021_Human
#> 106 KEGG_2021_Human
#> 107 KEGG_2021_Human
#> 108 KEGG_2021_Human
#> 109 KEGG_2021_Human
#> 110 KEGG_2021_Human
#> 111 KEGG_2021_Human
#> 112 KEGG_2021_Human
#> 113 KEGG_2021_Human
#> 114 KEGG_2021_Human
#> 115 KEGG_2021_Human
#> 116 KEGG_2021_Human
#> 117 KEGG_2021_Human
#> 118 KEGG_2021_Human
#> 119 KEGG_2021_Human
#> 120 KEGG_2021_Human
#> 121 KEGG_2021_Human
#> 122 KEGG_2021_Human
#> 123 KEGG_2021_Human
#> 124 KEGG_2021_Human
# }