Convert a marker table to the UCell signature format

A named list of gene vectors, one per cell type, in the UCell signature format.

Usage

markers_to_ucell_list(df)

Arguments

df

A canonical marker table.

Value

A named list of gene vectors, named by the cell types.

Details

UCell reads the marker direction from the gene name: a gene whose name ends in - is a negative marker (it contributes w_neg times its score, subtracted), while a trailing + is stripped. Negative-direction rows therefore get a - appended to the gene symbol and positive rows pass through unchanged. UCell has no per-gene weights, so a weight column is deliberately ignored.